Anirban Mitra, PhD
Microenvironment Induced Epigenetic Regulation in Ovarian Cancer
The spreading of cancer cells from the primary ovarian tumor to distant organs within the abdomen is the most critical step in ovarian cancer. Yet it remains the least understood aspect of the disease. Using unique and clinically relevant experimental models, including primary human cells, that replicate the early steps of metastatic tumor formation in patients, Dr. Mitra will investigate a novel mechanism of gene regulation that promotes metastasis. This will improve our understanding of the regulation of this key step and will help us to develop novel and effective therapies for ovarian cancer.