Ilona Kryczek, PhD
University of Michigan
IL-17+ T cells in patients with ovarian cancer
T helper cells (Th), a sub-group of white blood cells, play a crucial role in inflammatory responses and autoimmune diseases, but are poorly understood in human pathology. By using our well-established human ovarian cancer model, we propose to map out the basic knowledge of the nature of IL-17+ T cell in human ovarian cancer. Our project will lay a conceptual framework by which Th17 biology may be used to develop new strategies to treat human cancers.