Jason Wilken, PhD
sErb83: A novel ovarian cancer prognostic biomarker
A well-studied growth regulator in the development of ovarian cancer is the “oncogene” known as ErbB3/HER-3. There are several naturally-occurring variants of ErbB3 which are difficult to distinguish by currently available methods. We believe that developing accurate and specific tests for each ErbB3 variant will allow physicians to make predictions about the aggressiveness of a given ovarian tumor, whether the tumor will respond to a given treatment, and whether the patient will relapse following treatment.