Terry Van Dyke, PhD and Vickie Bae-Jump, MD, PhD
The University of North Carolina at Chapel Hill
A Pathway to Therapeutic Treatment and Early Detection of Ovarian Cancer
This project will compare global gene expression patterns across human and a novel genetically engineered mouse model of epithelial ovarian cancer in order to identify relevant molecular pathways and candidate genes that are essential for ovarian cancer development. This unique approach of cross-species comparisons should lead to the discovery of early markers of detection and novel therapeutic targets for drug development that are much needed for this disease.
