Dalibor Blazek, PhDMasaryk University (Czech Republic) The Roles of Cdk12 in Ovarian Tumorigenesis Recent comprehensive genomic analyses of patient samples have revealed the virtually unstudied cyclin-dependent kinase 12 (Cdk12) as a novel player in ovarian tumorigenesis. Dr. Blazek has already determined that Cdk12 maintains genome stability via the transcriptional regulation of key DNA-damage response genes, […]
Read MoreMatjaz Barboric, PhDUniversity of Helsinki Examining the Tumor Suppressor Function of Cdk12/CycK Kinase in Ovarian Cancer Failure to understand key mechanisms contributing to the onset of high-grade serous ovarian cancer represents a barrier to diagnosis and treatment of this fifth-leading cause of death among American women. One of the likely factors promoting the disease is […]
Read MoreNuzhat Ahmed, PhDWomen’s Cancer Research Center (Australia) Determining the MicroRNA Signature of Isolated Chemoresistant Ascites Tumor Cells Despite advances in treatment, almost 80% of ovarian cancer patients suffer disease recurrence and succumb to the disease within 5 years of diagnosis. Cancer stem cells are a small population of drug resistant tumor cells that survive chemotherapy […]
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