Jian-Jun Wei, MDNorthwestern University MiR-182 Overexpression in Early Tumorigenesis of High Grade Serous Carcinoma High grade papillary serous carcinoma may arise from serous tubal intraepithelial carcinoma in the fallopian tube. MiR-182 is a small RNA molecule that is significantly overexpressed in both types of carcinomas. Dr. Wei hypothesizes that miR-182 overexpression is a critical and […]
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Bin Zhang, MD, PhDNorthwestern University Treating ovarian cancer with novel ecto-5’nucleotidase (CD73) inhibitors Tumors have elaborate suppressive mechanisms against host immune system to enhance their survival. Ovarian tumors highly express a protein called CD73 that limits anti-tumor immune response in order to promote tumor growth. Dr. Zhang‘s recent research demonstrates that CD73 may serve as […]
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