Xuefang Cao, MD, PhDRoswell Park Cancer Institute Granzyme B-Dependent Regulatory T Cell Function in Ovarian Cancer While effector lymphocytes are known to mediate anti-tumor immune responses, regulatory T cells (Tregs) have recently been found to promote tumor progression in ovarian cancer patients. Perforin and granzyme B are cytotoxic molecules previously known to be utilized by […]
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Gokul Das, PhD, MPhil, MSRoswell Park Cancer Institute Functional analysis of mutant p53-estrogen receptor beta signaling crosstalk in high-grade serous ovarian cancer High-grade serous ovarian cancer is strikingly similar to triple negative breast cancer as both can be particularly aggressive cancers and are likely to recur. Dr. Das has found that these two diseases are […]
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