John Paul Shen, MDUniversity of California, San Diego Improving Outcomes in Ovarian Cancer: A Network Genomics Approach Technological advances now allow for sequencing of tumors from large patient cohorts. However, this knowledge of the cancer genome has not yet been translated into the clinical practice of oncology. Dr. Shen works in the Ideker lab which […]
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Identification of drugs that increase cisplatin uptake by inhibiting CTR2 CTR2 has shown to be a particularly attractive target against which to develop a drug that both inhibits tumor growth and sensitizes to platinum drugs. In this project, Dr. Howell will establish a robust assay to evaluate the function of CTR2 that can be used […]
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Stephen Howell, MDUniversity of California San Diego Dendrimer-folate targeting of paclitaxel to ovarian cancer Paclitaxel is used extensively for the treatment of ovarian cancer. The overall goal of this project is to test the efficacy and toxicity of a novel paclitaxel drug delivery system, capable of selectively targeting ovarian cancers and thereby increasing tumor cell […]
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