Jill Slack-Davis, PhDUniversity of Virginia Role of VCAM-1 in an orthotopic mouse model of ovarian cancer metastasis It is believed that the vascular cell adhension molecule-1 (VCAM-1) aids in the adhesion and spreading of ovarian cancer in the abdomen and beyond. By defining the role of VCAM-1, this work could lead to a target for […]
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Neveen Said, MD, PhDUniversity of Virginia Regulation and Function of SPARC in Ovarian Cancer Epithelial Ovarian cancer (OvCa) is the leading cause of death from gynecologic malignancies. Despite aggressive treatment, recurrence is common with poor survival. Dr. Said has recently reported the loss of expression of the tumor suppressor of the glycoprotein SPARC in advanced […]
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Jill Slack-Davis, PhDUniversity of Virginia Detailed characterization of tumor initiation in a novel mouse model of high-grade serous ovarian cancer Early detection remains the best approach for successful treatment of cancer, including ovarian cancer, as patients with early stage cancer have the best chance of survival. There is an urgent need to identify specific biomarkers […]
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Hui Zong, PhDUniversity of VirginiaCharlottesville, VA, United States 2019 Pilot Study Award Research in Focus: Prevention of ovarian cancer Efficacy testing for ovarian cancer prevention at pre-malignant stages with a novel mouse model Prevention remains the ultimate goal for successful management of cancer. Identifying cancer prevention strategies is challenging due to the large population required to […]
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