Sachdev Sidhu, PhDUniversity of TorontoToronto, Ontario, Canada 2019 Pilot Study Award Research in Focus: Novel therapies to treat ovarian cancer Targeting Ephrin receptors with antibody-drug conjugates to design novel treatments for ovarian cancer Alterations in certain proteins located on the surface of cells, known as receptor proteins, can lead to the formation of tumors. These receptor […]
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Keren Levanon, MD/PhDSheba Fund for Health Service and Research2019 Pilot Study Award Microbiome profiling unveils metabolic vulnerabilities of BRCA mutated ovarian cancer Recent studies have shown that fallopian tubes and other genital track tissues that were previously thought to be sterile actually contain bacteria. These bacteria are believed to cause chronic inflammation which can lead […]
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Christopher J. Kemp, PhDFred Hutchinson Cancer Research Center 2019 Sequoyah Electric Pilot Study Award Preclinical advancement of combination therapy targeting BAZ2A and EZH2 in ovarian clear cell carcinoma Ovarian cancer accounts for over 14,000 deaths in the United States every year. Although ovarian cancer has several subtypes, patients have been treated almost in the same […]
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Caroline Ford, PhDUniversity of New South Wales2019 James A. Harting Pilot Study Award Research in Focus: Novel therapies to treat ovarian cancer Shock and ROR! Inhibiting ovarian cancer metastasis with targeted therapies in an organotypic model of ovarian cancer In order to improve survival in ovarian cancer, we need to further study the molecular changes at […]
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André Lieber, MD, PhDUniversity of Washington2016 Lester and Bernice Smith Challenge Award Grant Immuno-Prophylaxis of Ovarian Cancer Associated with High-Risk Germ Line Mutations Dr. Lieber’s project proposes a prophylactic gene therapy approach to introduce genes encoding antibodies into hematopoietic stem cells from the bone marrow. Ovarian cancer cells normally produce signals that inhibit immune cells […]
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