Amelie Margarete Lutz, MD, PhDStanford University2009 Gilman Family Scholar Early Detection of Ovarian Cancer Using Targeted Microbubble-Enhanced Ultrasound The primary objective of Dr. Lutz’s proposal is to validate and refine molecularly targeted microbubble contrast enhanced ultrasound (CEUS) for non-invasive, in-vivo imaging of the ovarian cancer-related angiogenesis. Like other solid tumors, ovarian cancer is critically dependent […]
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John Liao, MD, PhDUniversity of Washington2011 Gilman Family Scholar Development of a Polyepitope DNA Vaccine for Ovarian Cancer Immunotherapy While ovarian cancer patients can respond to chemotherapy and achieve remission, the majority of advanced stage patients succumb to recurrent disease. Strategies harnessing the immune system have the potential to augment available therapies, prolong remissions, and […]
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Anne Noonan, MB BCh BAO, MSc, MRCPINational Cancer Institute2012 Gilman Family Scholar Proteomic biomarker development for optimal sequencing of doxetaxel & SMACmimetic The drug TL32711 can stimulate ovarian cancer cell death by decreasing proteins that inhibit cell death and decreasing signaling through the NFkB signalling pathway that is known to be overactive in ovarian cancer. […]
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Jessica Bertout, PhD, VMDFred Hutchinson Cancer Research Center2013 Gilman Family Scholar High-Resolution Detection of Somatic Ovarian Cancer Mutations in Bodily Fluids Owing to a lack of effective screening tests, 80% of ovarian cancer patients are diagnosed in late stages of the disease at which point there are low survival rates. Methods that enumerate tumor cells […]
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